Roche Integra 400 Plus Chemistry Analyzer
Integra 400+ Chemistry Analyzer by Roche Diagnostics
Roche Integra 400 Plus
The pressure for laboratories to work more efficiently has never been higher, increasing the need for innovative solutions. With the COBAS INTEGRA 400 plus, innovation means 4 on-board measurement technologies, robotic handling of reaction cuvettes and improved operator ergonomics. This supports the very broad menu and ease-of-use required for true workload consolidation, leading to efficiency gains only possible with only one analytical platform, one user interface & one reagent system.
COBAS INTEGRA
Manufactured by Roche Diagnostics, COBAS INTEGRA 400 plus is the perfect chemistry analyzer for laboratories with a throughput of 25,000 to 250,000 tests per year or 50 to 250 samples per day. A compact benchtop system for labs with limited floor space, this unit is designed to consolidate testing and increase efficiency while reducing total running costs of the laboratory. It is the right choice for consolidation in the low workload laboratory and special chemistry testing in medium volume sites.
The system's broad test menu comprises over 120 assays and applications that consolidate clinical chemistry with specific proteins, therapeutic drug monitoring and drug of abuse testing. It uses convenient cobas c pack reagent format which standardizes patient results across integrated laboratory networks.
System Functions and Workflow
This analyzer's extensive assay menu and innovation of the cobas c pack are combined with four proven measurement technologies and sophisticated, easy-to-use software. Each cobas c pack holds all necessary reagents for up to 800 determinations, maximizing on-board capacity and reducing the need for operator intervention and frequent reloading. The bar-coded cobas c packs are automatically handled by the system, reducing the possibility of errors and saving staff time. The system has up to 36 different on-board assays. For quick access to additional tests, cobas c packs can be exchanged while the system is running. Off-board storage of pre-calibrated packs allows full flexibility.
Features
Serum, plasma, urine, hemolysate, whole blood and CSF can be used in barcoded primary or secondary tubes. Microcups can be used for low volume samples. This analyzer also features:
- Comprehensive testing capabilities on a compact footprint
- Throughput of up to 400 tests/hour
- Highly sensitive pressure sensors detect incorrect pipetting, even at 2 µL sample volume
- Long on-board reagent stability and fewer calibrations mean less waste and lower cost per reportable result
- Configurable start-up options ensure that the system is ready whenever needed
- System wash pressures have been optimized to fully remove the clot from the sample probe, avoiding maintenance actions and interruptions to workflow
- Onboard capacity of 8 racks with 4 cobas c packs each
- 6 sample racks for various primary and secondary cups
- Positive sample identification via barcode
- Object-oriented system software based on Windows XP, for standardized ease-of use
The system's processing time can be reduced by up to 50% compared with dedicated chemistry analyzers. Its on-screen inventory management tracks reagents available on board and forecasts if additional reagent packs are required based on daily workload statistics.
Its intelligent processing automatically schedules each sample's tests to minimize analyzer turnaround time and increase throughput, while allowing immediate STAT testing 24 hours a day. Refurbished models of this analyzer are available at online stores of professional lab equipment suppliers.
Specifications
System
| Random and continuous access, sample selective analyzer Integration of 4 measuring principles 36 tests onboard Absorbance photometry: Enzymes and substrates Turbidimetry: Specific proteins, drugs of abuse Fluorescence polarimetry: Therapeutic drugs, thyroid tests Ion-selective electrode potentiometry: Na+,K+,Cl– and Li+ |
Test throughput
| Up to 400 tests/hr (including ISE) |
Sample types
| Serum, plasma, urine, CSF, hemolysate and whole blood (HbA1c) |
Sample handling
|
90 primary or secondary tubes on-board
Up to 6 x RD15 racks on-board
Cooled rack position for controls and calibrators
Automatic sample dilution and concentration
Barcode reading via laser scanner, with immediate STAT recognition
|
Sample container types
| Primary tubes: 5 to 10 mL; 16x100, 16x75, 13x100, 13x75 mm with closed cap for Hitachi microcup, 500 µL; Hitachi standard cup, 1.5 mL; cobas cup, 650 µL; Eppendorf cup, 1.5 mL; Cup on tube definable |
Sample volume
| Typically 2 to 10 µL per test, ISE indirect 20 µL, ISE direct 97 µL |
Sample barcode types
| Code 128, Codabar, Code 2 of 5 interleaved, Code 39 |
Reagents onboard capacity
| 32 cobas c packs, 50-800 tests per cobas c pack Up to 8 racks of 4 cobas c packs on-board Reagent compartment cooled to 10-15°C Onboard stability up to 3 months, calibration typically each lot |
Reaction cells
|
Holds 1,000 disposable cuvettes with 5 mm path length,
and 120-240 µL reaction volume
|
Control unit
| HP workstation running Windows XP Intel Pentium IV with 512 MB RAM Dual 40 GB hard drives, CD ROM, floppy drive and inbuilt modem |
System interfaces
| RS 232 serial interface, bi-directional, inbuilt modem for remote diagnostics access |
Electrical requirements | 100-125/200-240 Volts AC, 50 or 60 Hz, consumption 1,200 VA |
Physical dimensions | Width: 135 cm (53.1 in) Depth: 66 cm (25.9 in) Height: 75 cm (28.5 in) |
Weight | 320 kg (506 lbs) |
Water requirements | Up to 2 liters per hour in operating mode, Type 1 NCCLS |
Certification | CE, UL, C-UL |
