Herpes Simplex 1 IgA ELISA, 96 Wells
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Manufacturer: DRG International Inc.
Model: Herpes Simplex 1 IgA ELISA, 96 wells
Product Code: EIA2532
Block Scientific is a reputable distributor in the United States, offering a fine line of lab equipment for sale including chemistry analyzers, hematology analyzers, centrifuges, histology equipment, reagents and consumables. Based in Bellport, New York, we offer the Herpes Simplex 1 IgA ELISA, 96 wells and other infectious disease kits at competitive prices.
– Useful, Quality ELISA
The Herpes simplex virus 1 IgA is a useful, quality Enzyme Immunoassay Kit that provides materials for the quantitative determination of human IgA/IgG/IgM antibodies against Herpes simplex virus 1 (HSV 1) in serum and plasma.
The Herpes simplex virus type 1 is an ubiquitous pathogen of humans that usually causes either asymptomatic infection or mild skin and mucosal diseases. Antibodies to HSV 1 occur in about 90% of adults. Normally HSV 1 is transmitted by oral secretions or open wounds prior to the age of five. Recently in adults primary infections were observed, too.
After the primary infection some viruses establish a latent state in their host cells (mostly ganglial cells). The virus DNA is integrated into the genome of the host cell, where it remains until the infected person dies. After stimulation of the host cell, recurrent infection occurs, which is called an exacerbation, when clinical symtoms appear. The recurrence may be caused by different kinds of traumas, as fever or physiological changes and diseases. Immunosuppressed persons may show a severe clinical course.
HSV 1 causes different clinical symptoms in about 10% of the primary infections. The major clinical manifestations associated with HSV 1 infections are gingivostomatitis, keratitis, conjunctivitis, vesicular eruptions of the skin, encephalitis, eczema and some letal infections of newborns. HSV 1 causes 85% and HSV 2 15% of oral primary infections. Recurrent infection occurs in form of labial fever blisters. After ulceration and scabbing of these blisters complete recovery occurs within 10 days. The central nervous system may be involved in both primary and recurrent infections. In some cases HSV 1 infection leads to a meningitis with different neurological symptoms. Persons at an increased risk for serious or prolonged HSV infections are those with eczema, severe burns or a defect in their cell-mediated immunity. The drug Acyclovir is the treatment of choice for most serious HSV infections.
The common manifestations of HSV infections are so typical that the infection may be easily diagnosed on clinical recognition alone. The “gold standard” for diagnosis of HSV infection remains isolation of the virus in tissue culture. For typing HSV 1/HSV 2 Western blots or indirect immunofluorescence may be performed.
Diagnosis of the primary infection by HSV 1/HSV 2 can be confirmed by a significant rise of the IgG titer within 6 to 10 days. A finished infection can be monitored by the IgG ELISA. In case of a suspicion of HSV encephalopathy it is recommended to perform a parallel determination of both HSV-specific antibodies (IgG and IgM) in serum and liquor.
INTENDED FOR IN VITRO USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
- Test Kit Contents – microtiterwells, cut-off control, negative control, positive control, sample diluent, enzyme conjugate, stop solution, substrate solution, wash solution
- Storage – When stored at 2 °C to 8 °C, unopened reagents will retain reactivity until expiration date.
For more information on the Herpes Simplex 1 IgA ELISA, 96 wells and other infectious disease kits, please make a call to 631-589-1118, or send an e-mail to firstname.lastname@example.org. To view other products we carry, please browse through our online store.