Vitamin D helps maintain normal blood levels of calcium and phosphorous and is essential for overall bone health, to promote healthy growth and in disease prevention. An adequate level of vitamin D level is crucial for the optimal functioning of tissues and cells, and to reduce the risk of bone fractures, autoimmune diseases, type 2 diabetes, cancer, hypertension, immune dysfunction, and inflammation. Vitamin D insufficiency increases the risk of cardiovascular diseases, and leads to osteomalacia in adults and rickets in children. Vitamin D testing helps in the prevention of these acute and chronic diseases.
Vitamin D Assays
Although liquid chromatography-tandem mass spectrometry (LC-MS) is considered the gold standard technology for vitamin D testing, measurement of serum 25(OH)D levels is frequently performed using immunoassays. Two most commonly used laboratory tests for vitamin D are: 25-hydroxy vitamin D or 25(OH)D, and 1,25-dihydroxyvitamin D.
Diazyme Laboratories’ 25-OH Vitamin D Assay is both fast and flexible. It requires only 20 uL of sample and returns patient results within 19 minutes. This assay is a liquid-stable, three-reagent system intended for the quantitative determination of 25-hydroxyvitamin D (25-OH-D) in human serum and plasma on automated chemistry analyzers such as Roche’s Cobas Mira, Roche Integra 400, and more.
According to a recent Technavio market survey, the vitamin D testing market in Europe to grow at a CAGR of more than 5% during the period of 2015-2019. The report notes the 25-Hydroxy vitamin D test as the largest market segment during the forecast period. The main reason for this market segment’s high growth is the ability of this test to identify bone malformations and softness, bone weakness, or fractures in adults. This segment had a massive share of 77% in 2014 and this trend is expected to continue during the forecast period. Key players in the market include Diazyme Laboratories, Roche Diagnostics, Beckman Coulter, Quest Diagnostics Inc., Abbott Diagnostics, and Siemens Healthcare Diagnostics.