Badly fitting pipette tips allow air to escape when drawing up and dispensing, thus leading to inaccurate results. Different types of tips are now available in the market – extended length pipette tips that can reach to the bottom of sample vessels without contact by the pipette, solvent safe carbon filtered tips that offer pipette and sample protection against aggressive aerosols and vapors from volatile organic solvents, wide orifice tips designed to eliminate cell sheering and flow resistance, individually wrapped tips for applications requiring stringent aseptic conditions, gel loading tips, sterilized filter tip to prevent aerosol contamination, and low retention tips designed for applications requiring high accuracy and reproducibility. The choice of tip depends primarily on the dispensing volume set on the pipetting head.
Here are some important factors to consider while choosing pipette tips:
- Consider the physical properties of your sample, the type of analysis you are performing and the volume range required to determine which pipette and tip you should use
- Make sure that the chosen tip properly fits your equipment.
- Check whether there sealing rings between the tip and pipette that can minimize leaking, increase accuracy, and reduce error during testing
While transferring single samples of different liquids, it is recommended to select a new pipette tip for each new liquid and to pre-rinse every new pipette tip.
The automation pipette tips provided by leading manufacturers such as Thermo Scientific abide to quality control standards and are validated on the instruments they will be used on. They also ensure accuracy and precision and are engineered for safety. For instance, there are tips that can be removed from the pipette using the tip ejector button, without the user having to touch any hazardous material. Known for offering superior analytical instruments, laboratory equipment, software, services, consumables and reagents, Thermo Scientific offers over 200 automation tip designs to fit more than 50 different instrument and pipetting head variations.